ReproRank mines pharmaceutical patents and shows you the protocols that independent organisations used on substrates like yours, with the evidence behind each one.
Built by a medicinal chemist, for medicinal chemists. Now in pilot.
A patent tells you what worked once, for one team, on one substrate. When unrelated companies converge on the same catalyst, base and solvent for similar substrates, that protocol has been tested by many hands. ReproRank counts that convergence for you.
Paste your electrophile and boron partner, or the product. ReproRank finds structurally similar couplings in the patent literature.
Only complete procedures are shown and ranked by how many independent organisations used them on substrates like yours.
Instead of a list of 200 hits to sort through, you now leave with the best-supported protocol to try first and a backup or two. Set it up and go.
I have spent over twenty-five years in medicinal chemistry, and a painful share of that time repeating literature conditions that worked beautifully on paper and refused to work at the bench.
ReproRank started as my own answer to a simple question: of everything published, what has been reproduced? Every grouping decision in the dataset, what counts as the same chemistry, was made by hand.
The pilot is free. You get a personal link and can run as many searches as you like for 30 days. Published or patented chemistry is ideal; nothing confidential is needed.
Request pilot access · pilot@reprorank.comStructures and names you enter are never stored, not even as a hash. Hosted in the EU.
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